Author: Shawn Gomez

bioRxiv – Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer

A preprint describing our work with Gary Johnson’s group on defining the baseline kinome in breast cancer is now out on bioRxiv. Collins KAL, Stuhlmiller T, Zawistowski JS, East MP, Pham T, Hall CR, Goulet DR, Bevill SM, Angus SP, Velarde SH, Sciaky N, Graves LM, Johnson GL, Gomez SM. Proteomic Analysis Defines Kinase Taxonomies Specific For Subtypes Of Breast Cancer. bioRxiv doi:...

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New award to develop a gut-on-a-chip!

With Nancy Allbritton, Scott Magness and Scott Bultman, we have just received a 5-year NIH Transformative Research Award for the development of a human intestinal simulacra! Essentially a “gut-on-a-chip”, this work will establish a novel platform that simulates a human colon epithelium within a highly controlled engineered environment. Creating this simulacra will not only allow the study of the basic colon physiology, but also enable the manipulation and study of introduced microbial communities, dietary factors and drugs that are relevant to the maintenance of health and the establishment of disease in this organ. My group will be doing the informatics for the project, including the “traditional”...

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Coverage of our Engineering Solutions to Health Problems workshop

In April, I headed up the development and organization of an all-day workshop focused on bringing together clinicians and scientists/engineers to focus on the identification of unmet clinical needs. There was a huge amount of interest, with enough demand that we had to setup a waitlist. Needs were looked at in three major themes that included mHealth, Rehabilitation Engineering and Clinical Devices, with a fourth “wild-card” theme that dealt with other technology areas. A wide variety of needs were identified and fleshed out during the course of the day, with a subset being ranked as high-priority and being followed up...

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Announcing the i4 Program

The i4 Program is a novel initiative within the Joint Department of Biomedical Engineering that melds traditional undergraduate engineering education with biomedical entrepreneurship. Composed of four phases of need Identification, Ideation, Innovation and Implementation, this mentored design program culminates in an annual competition awarding a financial prize that supports further intellectual property development and the eventual formation of a student-founded company. Bringing talented students together with highly accomplished academic, clinical and industry professionals, the i4 Program drives young, innovative entrepreneurship into the Triangle region while fostering the creation of practical solutions to real-world problems. Dates and other important information...

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Bioimage informatics paper on automated invadopodia analysis selected as a “Top Cancer Biology Paper” in PeerJ

We are happy to announce that our paper on the Automated Analysis of Invadopodia Dynamics in Live Cells (https://peerj.com/articles/462/?td=bl) was recently selected as one of the “Top 10” cancer biology papers for 2015 in PeerJ (https://peerj.com/collections/20-cancer-biology-july-2015/).We were also happy to make this paper initially available as a preprint (https://peerj.com/preprints/320/?td=bl). Many other exciting and high-quality papers are part of this collection, so have a...

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The Gomez Lab

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